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Lux Bio Group, Inc. · Camas, Washington

A pore, a channel, and a single molecule passing through.

Lux Bio Group, Inc. developed a nanochannel device for separating, purifying and sensing molecules — a support material with a channel through it, electrodes on the channel wall, and a lipid bilayer holding one protein nanopore.

Support material Nanochannel Sidewall electrode Nanomembrane & nanopore Lipid bilayer, single protein pore Molecules in Molecules out
Schematic of the device described in US 10,422,000 B2. A drawing, not a photograph.

What it was

Molecular work, done in a channel

The patent describes a device, not a product. Molecules are driven along a nanochannel; a nanomembrane inside the channel carries a nanopore; a lipid bilayer spans that pore with a single protein nanopore inserted into it, sized so that only one pore fits.

That geometry is the whole idea: confine the read to one molecule at a time.

The record, in short

  • EntityLux Bio Group, Inc.
  • IncorporatedWashington, 2010
  • BasedCamas, Washington
  • PatentUS 10,422,000 B2
  • Priority2 April 2012

Three capabilities

Separate, purify, sense

Molecular separation

Sorting molecules by size and charge at the nanoscale, in a channel rather than a column.

Purification

Concentrating a target molecule out of a mixed sample.

Sensing

Detecting molecules as they pass a single protein nanopore, read electrically.

How it reads

Three stages, one channel

Separate

Molecules are driven along the nanochannel, where size and charge decide how they move.

Purify

The pore geometry concentrates what passes and holds back what should not.

Sense

The electrodes read the pore, and the protein pore gives the device its single-molecule resolution.

Contact

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The company published one address and one telephone number. Both are reproduced, as they stood.

Lux Bio Group, Inc.

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